Modified hyaluronic acid for use in musculoskeletal tissue repair
US7091191B2 · kind B2 · utility
782Cited by
8References
6Claims
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Key dates
| Filing date | Dec 19, 2003 |
| Grant date | Aug 15, 2006 |
| Priority date | — |
| Expiry date | Oct 1, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/728
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention includes hyaluronic acid complexes of a monovalent alkali metal salt of hyaluronic acid and a tetra alkyl ammonium halide that are suitable for incorporation with tissue scaffolds that are suitable for use in repair and/or regeneration of muscoloskeletal tissue and that include a biodegradable, porous substrate made from a biodegradable, hydrophobic polymer, where the hyaluronic acid complex is substantially insoluble in water at room temperature, yet soluble in mixtures of organic and aqueous solvents in which the selected hydrophobic polymer is soluble.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.