Compounds substituted with bicyclic amino groups
US7091352B2 · kind B2 · utility
2Cited by
2References
18Claims
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Key dates
| Filing date | Jul 22, 2003 |
| Grant date | Aug 15, 2006 |
| Priority date | — |
| Expiry date | Oct 13, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula (I) below, or pharmacologically acceptable salts, esters or other derivatives thereof:wherein A is furan, thiophene, pyrazole, imidazole, isoxazole or isothiazole; R1 is a substituted or unsubstituted aryl or a substituted or unsubstituted heteroaryl; R2 is a substituted or unsubstituted heteroaryl; and R3 is a bicyclic amino group; provided that the substituents R1 and R2 are bonded to the two atoms of the cyclic group A which are adjacent to the atom of the cyclic group A to which the substituent R2 is bonded. The compounds inhibit the production of inflammatory cytokines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.