Process for the industrial synthesis of tetraesters of 5-[bis(carboxymethyl)amino]-3-carboxymethyl-4-cyano-2-thiophenecarboxylic acid, and application to the synthesis of bivalent salts of ranelic acid and their hydrates
US7091364B2 · kind B2 · utility
4Cited by
5References
12Claims
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Key dates
| Filing date | Sep 24, 2003 |
| Grant date | Aug 15, 2006 |
| Priority date | — |
| Expiry date | Apr 29, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The process for the industrial synthesis of compounds of formula (I):wherein R and R′, which are the same or different, each represent linear or branched (C1–C6)alkyl.Application to the synthesis of bivalent salts of ranelic acid and more especially strontium ranelate and its hydrates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.