N-biphenylmethyl aminocycloalkanecarboxamide derivatives

US7091380B2 · kind B2 · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Michael R. Wood · Harleysville, US
• Neville J. Anthony · Hatfield, US
• Mark G. Bock · Hatfield, US
• Dong-Mei Feng · Harleysville, US
• Scott D. Kuduk · Harleysville, US
• Dai-Shi Su · New York, US
• Jenny Wai · Harleysville, US

Key dates

• Filing date: Feb 4, 2003
• Grant date: Aug 15, 2006
• Expiry date: Feb 8, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

N-Biphenyl(substituted methyl) aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.