Method for making cytokine specific antibodies and uses thereof
US7094396B2 · kind B2 · utility
0Cited by
1References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 8, 2003 |
| Grant date | Aug 22, 2006 |
| Priority date | — |
| Expiry date | Jul 27, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/6081
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The methods of this invention relate to immunizing animals with conjugates of cytokines and a carrier to induce a prolonged high titre antibody response specific for the cytokine. This invention also relates to the treatment of pathological conditions, e.g., eosinophilia and allograft rejection, associated with the production of cytokines, in particular interleukins, e.g., IL-4, IL-5, IL-9, and IL-13, by immunization with the cytokine conjugates or by administration of antibodies specific for the cytokine. This invention also relates to compositions comprising the cytokine conjugates and the conjugates per se.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.