Recombinant adenoviral vectors expressing chimeric fiber proteins for cell specific infection and genome integration
US7094398B1 · kind B1 · utility
10Cited by
1References
25Claims
0Family size
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Inventors
Key dates
| Filing date | Jun 1, 2000 |
| Grant date | Aug 22, 2006 |
| Priority date | — |
| Expiry date | Jun 17, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/80
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides for novel chimeric Ad-vectors carrying transgene, or portions of transgenes for stable and efficient gene transfer into diverse cell types or tissues in a CAR- and/or αυβ3/5-independent manner. Also provided are methods for producing such vectors and the use thereof for gene therapy to target a specific cell type or tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.