Patent · US Expired

Poxvirus containing formulations and process for preparing stable poxvirus containing compositions

US7094412B2 · kind B2 · utility

1Cited by

6References

20Claims

0Family size

Assignee

Bavarian Nordic A/S · DK

Inventors

Paul Howley · Scone, AU
Karl Heller · Unterföhring, DE
Ingmar Rathe · Olching, DE

Key dates

Filing date	Nov 28, 2002
Grant date	Aug 22, 2006
Priority date	—
Expiry date	Nov 28, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2710/24034
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a formulation, in particular an aqueous formulation comprising (i) a poxvirus of one of the genera orthopoxvirus, avipoxvirus, parapoxvirus, capripoxvirus and suipoxvirus, (ii) a disaccharide, (iii) a pharmaceutically acceptable polymer and optionally (iv) a buffer. The aqueous formulation is particularly suitable for freeze drying processes resulting in a stable, freeze-dried, poxvirus containing composition. The invention further concerns a method for preparing a freeze-dried, poxvirus containing composition and the thus obtained product.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.