Assay to identify estrogen receptor dependent ligands that regulate the hepatic lipase promoter
US7094559B1 · kind B1 · utility
3Cited by
5References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 8, 2001 |
| Grant date | Aug 22, 2006 |
| Priority date | — |
| Expiry date | Aug 8, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/743
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to an assay system and method for testing compounds for their ability to regulate the hepatic lipase (HL) promoter. In particular, the invention relates to the identification of estrogen receptor ligands having this activity. Compounds that inhibit HL promoter activity are useful as leads, or on their own, to develop therapeutics in the prevention of heart disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.