Glial mitogenic factors, their preparation and use
US7094749B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 22, 1996 |
| Grant date | Aug 22, 2006 |
| Priority date | — |
| Expiry date | Oct 22, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/1883
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is the characterization and purification of DNA encoding a numerous polypeptides useful for the stimulation of glial cell (particularly, Schwann cell) mitogenesis and treating glial cell tumors. Also disclosed are DNA sequences encoding novel polypeptides which may have use in stimulating glial cell mitogenesis and treating glial cell tumors. Methods for the synthesis, purification and testing of both known and novel polypeptides for their use as both therapeutic and diagnostic aids in the treatment of diseases involving glial cells are also provided. Methods are also provided for the use of these polypeptides for the preparation of antibody probes useful for both diagnostic and therapeutic use in diseases involving glial cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.