Antisense restenosis composition and method
US7094765B1 · kind B1 · utility
84Cited by
7References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 29, 2000 |
| Grant date | Aug 22, 2006 |
| Priority date | — |
| Expiry date | Jan 29, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/07
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an improved method for reducing the risk or severity of restenosis following cardiac angioplasty. The method includes administering to a target vessel region, a morpholino antisense compound having uncharged phosphorus-containing backbone linkages, and spanning the start codon of a human c-myc mRNA. Also disclosed are novel antisense compounds and compositions, and a method for assaying the effectiveness of antisense delivery and uptake to a target vessel region.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.