Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus
US7094908B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Dec 23, 2002 |
| Grant date | Aug 22, 2006 |
| Priority date | — |
| Expiry date | Nov 12, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/48
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound represented by a general formula (Ia) or (Ib) and a stereo-selective preparation method thereof using a carbonyl reductase which is separated from Kluyveromyces marxianus. The compound can be prepared by reduction of substituted β-keto ester and can be used as an intermediate in preparing β-lactam group antibiotics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.