Method for detecting the presence of an analyte in a sample

US7097983B2 · kind B2 · utility

Assignee

• Charm Sciences, Inc. · US

Inventors

• Robert J. Markovsky · Brentwood, US
• Cheryl A. Boyer · Malden, US
• Stanley E. Charm · Boston, US
• Paul R. Donahue · Upton, US
• Yael Glickman · Eilat, IL
• Steven J. Saul · Arlington, US
• Joan L. Scheemaker · Chelmsford, US
• Richard T. Skiffington · North Reading, US
• Shefali B. Trivedi · Quincy, US
• Eliezer Zomer · Newton, US

Key dates

• Filing date: Sep 24, 2001
• Grant date: Aug 29, 2006
• Expiry date: Apr 12, 2022

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/105831
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention features a method of determining whether one or more members of an analyte family are present in a sample. The method makes use of a test zone binder, e.g., a receptor that can bind one or a plurality of analytes within an analyte family, the analytes family defined by similar structural binding sites. Members of an analyte family can have different detection level requirements and, therefore, additional analyte binders can be employed to adjust test sensitivity for a subset of the analytes in the analyte family individually, so that each analyte can be detected only if it is present in the sample above a predetermined threshold.