Patent · US Expired

Bicyclic-substituted amines having cyclic-substituted monocyclic substituents

US7098222B2 · kind B2 · utility

15Cited by
6References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 6, 2005
Grant dateAug 29, 2006
Priority date
Expiry dateMay 6, 2025

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula (I)wherein R1 or R2 is an aromatic or non-aromatic ring directly joined or joined by a linker, as represented by L2 and L3, to a heteroaromatic core, and X, X′, Y, Y′, Z, Z′, R1, R2, R3, R3a, R3b, R4, R5, L, L2, and L3 are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.