Patent · US Expired

System and method for automatically processing microarrays

US7099502B2 · kind B2 · utility

6Cited by
91References
76Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 21, 2004
Grant dateAug 29, 2006
Priority date
Expiry dateFeb 17, 2024

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG06T2207/30072
  • WIPO fieldComputer technology
  • WIPO sectorElectrical engineering

Abstract

A digital image processing-based system and method for quantitatively processing a plurality of nucleic acid species expressed in a microarray are disclosed. The microarray is a grid of a plurality of sub-grids of the nucleic acid species. The system includes a scanner that has a digital scanning sensor that scans the microarray and transmits from an output a digital image of the microarray, and a processor that receives the digital image of the microarray from the scanner and then processes the digital image, identifying each of the microarray's sub-grids. The processor then detects in each of the sub-grids a center-representing pixel of a signal of a chemical material and an approximate radius of the signal. Then, the processor segments the signal and calculates a characterizing measure for the segmented signal.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.