In situ maturation of cultured pancreatic stem cells having a specified, intermediate stage of development
US7101546B2 · kind B2 · utility
3Cited by
9References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 20, 2002 |
| Grant date | Sep 5, 2006 |
| Priority date | — |
| Expiry date | Mar 21, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K35/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the discovery that an intermediate, differentiated stage of pancreatic stem cells exist that can be matured in situ into a stable cell line that produces insulin in response to glucose. These cells are advantageous in that they are both expandable and stable in culture. This invention avoids the step of culturing the intermediate stage stem cells into later stage pancreatic cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.