Non-peptide GNRH agents, methods and intermediates for their preparation
US7101878B1 · kind B1 · utility
28Cited by
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8Claims
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Key dates
| Filing date | Aug 20, 1999 |
| Grant date | Sep 5, 2006 |
| Priority date | — |
| Expiry date | Aug 20, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, multimers, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. Methods for synthesizing the compounds and intermediates useful in their preparation are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.