2-guanidinylimidazolidinedione compounds and methods of making and using thereof
US7101902B2 · kind B2 · utility
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34Claims
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Inventors
Key dates
| Filing date | Nov 19, 2004 |
| Grant date | Sep 5, 2006 |
| Priority date | — |
| Expiry date | Nov 19, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein are 2-guanidinylimidazolidinedione compounds having the structural formula A or Bwherein R1 and R2 are each independently a hydrogen, halogen, alkyl, alkoxyl, amino, alkylamino or aralkyl, and wherein R3 is an alkyl, cycloalkyl, heterocycloalkyl, acyl, aryl, heteroaryl, alkylaryl, sulfonyl, alkylsulfonyl, and pharmaceutically acceptable salts thereof, and methods of making thereof. Also disclosed are methods of treating, preventing, or inhibiting malaria with the 2-guanidinylimidazolidinedione compounds, and pharmaceutical compositions comprising the 2-guanidinylimidazolidinedione compounds, and kits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.