Antibodies of the P2Y10 receptor useful in altering T lymphocyte function
US7101962B2 · kind B2 · utility
15Cited by
1References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 13, 2004 |
| Grant date | Sep 5, 2006 |
| Priority date | — |
| Expiry date | May 13, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/505
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to modulators of P2Y10. Various modulators are disclosed, including an antibody that binds specifically to P2Y10. The present invention also relates to methods of activating resting T lymphocytes and inhibiting the proliferation of activated T lymphocytes. Methods of upregulating trascription of P2Y10 mRNA in a resting T lymphocyte, methods of inducing expression of P2Y10 on the surface of a resting T lymphocyte and methods of activating a T lymphocyte are disclosed. Also disclosed are pharmaceuticals and methods of treating an immune disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.