DsrA protein and polynucleotides encoding the same
US7101989B1 · kind B1 · utility
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9Claims
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Key dates
| Filing date | Jul 7, 2000 |
| Grant date | Sep 5, 2006 |
| Priority date | — |
| Expiry date | Feb 23, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
DsrA is an outer membrane protein of H. ducreyi that confers serum resistance to the bacteria. Isolated polynucleotides encoding the protein, end expression vectors and host cells encoding the same, are described. Also described is a mutant H. ducreyi strain that does not express DsrA. Vaccines against H. ducreyi and methods of using the same are also described.
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