Patent · US Expired

Colonic polyp discrimination by tissue fluorescence and fiberoptic probe

US7103401B2 · kind B2 · utility

30Cited by
217References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 10, 2002
Grant dateSep 5, 2006
Priority date
Expiry dateJul 25, 2023

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61B5/4255
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at three selected wavelengths, about 403 nm, about 414 nm, and about 431 nm. The intensities of the 403 nm and 414 mn radiation are normalized using the 431 nm intensity. A score is determined using the ratios in a linear discriminant analysis (LDA). The tissue under examination is resected or not, based on the outcome of the LDA.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.