Cardiac drug delivery system
US7104988B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 19, 2002 |
| Grant date | Sep 12, 2006 |
| Priority date | — |
| Expiry date | Jun 19, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/0089
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A system is disclosed, for administering a therapeutic agent locally and to a depth within cardiac tissue. An elongate, flexible catheter contains a flexible electric conductor and supports at its distal end an implantable electrode incorporating a penetrating element, typically a fixation helix or a linear needle that penetrates cardiac tissue as the electrode is implanted. A therapeutic agent is delivered through the electrode, to the cardiac tissue surrounding the penetrating element. The electrode can act as a sensor, to monitor an electrical condition of the surrounding cardiac tissue, and to control delivery of the agent responsive to the sensed electrical condition. Several embodiments feature a distal reservoir adjacent the electrode for effecting transient deliveries of the therapeutic agent in minute quantities. Other embodiments are disclosed for providing sustained deliveries of the agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.