Methods for the production of tyrosine, cinnamic acid and para-hydroxycinnamic acid
US7105326B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | May 3, 2002 |
| Grant date | Sep 12, 2006 |
| Priority date | — |
| Expiry date | Oct 5, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/225
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Genes encoding phenylalanine ammonia-lyase (PAL), tyrosine ammonia lyase (TAL) and phenylalanine hydroxylase (PAH) have been introduced into a host organism for the production of Para-hydroxycinnamic acid (PHCA). The introduction of these genes results in the redirection of carbon flow in the host, optimizing the flow of carbon from glucose to PHCA. The intermediates, tyrosine and cinnamic acid are also produced.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.