Carbamate-substituted pyrazolopyridine-derivatives

US7105523B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Johannes-Peter Stasch · Solingen, DE
• Achim Feurer · Wilhelmsfeld, DE
• Stefan Weigand · Wuppertal, DE
• Elke Stahl · Bensberg, DE
• Dietmar Flubacher · Glückstadt, DE
• Cristina Alonso-Alija · Haan, DE
• Frank Wunder · Wuppertal, DE
• Dieter Lang · Velbert, DE
• Klaus Dembowsky · Boston, US
• Alexander Straub · Wuppertal, DE
• Elisabeth Perzborn · Wuppertal, DE

Key dates

• Filing date: Nov 9, 2001
• Grant date: Sep 12, 2006
• Expiry date: Mar 4, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P29/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to compounds of the formula wherein R1 is H or a di-C1-6-alkylaminocarbonyl raical, and R2 is a radical of the formula —O—C(X)—NR3R4 wherein X is O or S. A process for preparing such compounds, pharmaceutical compositions containing them, and methods for using them in treatment of hypertension are also disclosed and claimed.