Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex
US7105539B2 · kind B2 · utility
20Cited by
4References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 3, 2003 |
| Grant date | Sep 12, 2006 |
| Priority date | — |
| Expiry date | Jan 23, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06191
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula:useful as inhibitors of PHEX. These derivatives are useful for promoting generation of bone mass and treating or preventing diseases or conditions associated with a phosphate metabolism defect. Methods for preparation and intermediates are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.