cDNAs and proteins involved in hypoxia, circadian and orphan signal transduction pathways, and methods of use
US7105647B1 · kind B1 · utility
2Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 27, 1998 |
| Grant date | Sep 12, 2006 |
| Priority date | — |
| Expiry date | Nov 27, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4702
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides isolated nucleic acids and proteins that are new and distinct members of the bHLH-PAS superfamily of transcription regulators. These “MOPs” (members of PAS) are useful in a variety of research, diagnostic and therapeutic applications. Several of the MOPs of the present invention are α-class hypoxia-inducible factors. Several other of the MOPs of the invention are involved in circadian signal transduction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.