Patent · US Expired

Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide

US7105699B2 · kind B2 · utility

13Cited by
5References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 7, 2005
Grant dateSep 12, 2006
Priority date
Expiry dateSep 7, 2025

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2602/28
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.