Measuring technique

US7105823B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Christoffer Abrahamsson · Älvsbyn, SE
• Stefan Andersson-Engels · Dupnitsa, BG
• Staffan Folestad · Timrå, SE
• Jonas Johansson · Delta, CA
• Sune Svanberg · Lund, SE

Key dates

• Filing date: Mar 18, 2002
• Grant date: Sep 12, 2006
• Expiry date: Dec 30, 2022

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N21/359
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates to apparatuses for use in performing a quantitative analysis of a turbid pharmaceutical sample, e.g. a tablet, a capsule or a similar sample forming a pharmaceutical dose. A pharmaceutical, turbid sample (24, 57, 67) is irradiated with an excitation beam (20, 53, 64) of radiation, e.g. near infrared radiation. The intensity of emitted radiation (30) from the sample (24, 57, 67) is detected as function of both the wavelength of the emitted radiation and the photon propagation time through said sample (24, 57, 67). Optionally, the intensity of the emitted radiation (30) from the sample (24, 57, 67) is also detected in a spatially resolved manner.