Closed-loop drug delivery system
US7108680B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 6, 2002 |
| Grant date | Sep 19, 2006 |
| Priority date | — |
| Expiry date | Oct 1, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2205/50
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A delivery system for a drug or bioactive agent includes an implantable pump and a delivery conduit that may be implanted in an organ or other tissue (e.g., the central or the peripheral nervous system) of a subject. A sensor is also implanted, and a controller unit receives the sensor output and directs drug delivery from within the patient pump accordingly. The sensor directly measures a primary biochemical material or state in the tissue or organ system, and the monitoring unit effects closed loop feedback control of the pump to achieve a desired end. The end may be the regulation of metabolism or maintenance of a stable metabolic or other state, or may be treatment regimen, e.g., by delivery of a dosage level or distribution of a drug in specific brain or nervous an system tissue. The sensed material may be the agent itself, a metabolite, or a related native material, tissue state or condition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.