ATM kinase compositions and methods
US7108992B2 · kind B2 · utility
2Cited by
27References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 27, 2002 |
| Grant date | Sep 19, 2006 |
| Priority date | — |
| Expiry date | Aug 17, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods for detecting activation of ATM kinase, DNA damage, and DNA damaging agents. Further provided are antibodies which specifically recognize the phosphorylation state of Ataxia Telangiectasia-Mutated (ATM) kinase. Methods of identifying agents which modulate the activation and activity of ATM kinase are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.