Retro-inverso peptides derived from leukemia inhibitory factor
US7109168B1 · kind B1 · utility
1Cited by
6References
9Claims
0Family size
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Key dates
| Filing date | Jun 16, 2000 |
| Grant date | Sep 19, 2006 |
| Priority date | — |
| Expiry date | Mar 9, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/5415
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Retro-inverso peptides derived from leukemia inhibitory factor (LIF) having between 18 and about 40 amino acids and including the sequence shown in SEQ ID NO: 1. These peptides have the same activity as native LIF and also have neurotrophic activity. Because of the D-amino acid linkage in the peptides, they are less susceptible to proteolytic degradation in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.