Method for producing a bioactive bone cement and bone cement kit

US7109254B2 · kind B2 · utility

Assignees

• BAM Bundesanstalt fuer Materialforschung und-pruefung · DE
• Vita Zahnfabrik H. Rauter GmbH & Co. KG · DE
• Humboldt-Universitaet Berlin, Charite Universitaetsklinikum (CCM) Medizinische Fakultaet der Humbolt-Universitaet · DE

Inventors

• Wolf-Dieter Muller
• Emil Nagel · Annaberg-Buchholz, DE
• Georg Berger · Panketal, DE

Key dates

• Filing date: Jun 14, 2002
• Grant date: Sep 19, 2006
• Expiry date: Jun 14, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/02
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method for producing a bioactive bone cement and a bone cement kit for anchoring artificial joints and for filling out bone defects. The method avoids polymerization-linked by-products and disadvantageous effects, while at the same time providing the bone cement with long-term stability. The inventive method uses a monomer-free polymethylmethacrylate, which is mixed with a suitable non-toxic solvent, and a bioactive, vitreous-crystalline material with a particle size ranging from >20 to 200 μm, having 15–45 wt. % CaO, 40–45 wt. % P2O5, 10–40 wt. % ZrO2 and 0.7–3.5 wt. % fluoride, having apatite and calcium zircon phosphate as main crystal phases and a glass phase as an auxiliary component until a flowable mixture is obtained. The invention also relates to a bone cement kit having said components.