FAIL molecules and uses thereof
US7109319B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 10, 2003 |
| Grant date | Sep 19, 2006 |
| Priority date | — |
| Expiry date | Mar 10, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides isolated nucleic acid molecules, designated FAIL, which encode polypeptide molecules containing Ig and Ig-like domains and which are homologous to FcγRI. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.