Method and sensor for detecting the binding of biomolecules by shear stress measurement
US7112452B2 · kind B2 · utility
6Cited by
6References
18Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 23, 2002 |
| Grant date | Sep 26, 2006 |
| Priority date | — |
| Expiry date | Sep 25, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/806
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method and sensor are provided for detecting the binding of a probe and a target biomolecule by measuring a difference in the shear stress on the surface of the sensor before and after hybridization of the target molecule to the probe, such as nucleic acids or proteins. The shear stress may be measured sensitively and conveniently as an electrical signal without additional fluorescent labeling and without use of expensive additional devices.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.