Cysteine protease inhibitors with 2-cyano-4-amino-pyrimidine structure and cathepsin k inhibitory activity for the treatment of inflammations and other diseases
US7112589B2 · kind B2 · utility
9Cited by
2References
9Claims
0Family size
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Key dates
| Filing date | Aug 29, 2002 |
| Grant date | Sep 26, 2006 |
| Priority date | — |
| Expiry date | Aug 29, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compounds of formula I or a pharmaceutically acceptable salt or ester thereof (I), wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.