Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US7112603B2 · kind B2 · utility
29Cited by
26References
54Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 10, 2004 |
| Grant date | Sep 26, 2006 |
| Priority date | — |
| Expiry date | Jun 11, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65583
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to prodrugs of certain 3-(pyrrol-2-yl-methylidene)-2-indolinone derivatives that modulate the activity of protein kinases (“PKs”). Pharmaceutical compositions comprising these compounds, methods of treating diseases related to abnormal PK activity utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.