Processes for preparation of 9,11-epoxy steroids and intermediates useful therein

US7112669B2 · kind B2 · utility

Assignee

• Pharmacia Corporation (of Pfizer, Inc.) · US

Inventors

• John S. Ng · Chicago, US
• Chin Liu · Vernon Hills, US
• Dennis K. Anderson · Holden, US
• Jon P. Lawson · Park Hills, US
• Joseph Wieczorek · Cary, US
• Sastry A. Kunda · Chesterfield, US
• Leo J. Letendre · Oakdale, US
• Mark Pozzo · Chesterfield, US
• Yuen-Lung L. Sing · Chesterfield, US
• Ping T. Wang · Ballwin, US
• Edward Yonan · Carol Stream, US
• Richard M. Weier · Lake Bluff, US
• Thomas R. Kowar · Rantoul, US
• Julio A. Baez · San Diego, US
• Bernhard Erb · Gipf-Oberfrick, CH

Key dates

• Filing date: Feb 7, 2005
• Grant date: Sep 26, 2006
• Expiry date: Apr 20, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P33/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Intermediates in the preparation of 9,11-epoxy steroids are disclosed. Particularly, disclosed are 11,12-epoxy steroid, 4,5-9,11-diepoxy steroid and 12-keto steroid intermediates.