Process for the selective preparation of 3-(z) propenyl-cephem compound
US7112672B2 · kind B2 · utility
1Cited by
4References
15Claims
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Key dates
| Filing date | Apr 17, 2002 |
| Grant date | Sep 26, 2006 |
| Priority date | — |
| Expiry date | Dec 6, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 3-(Z)-propenyl cephem compound is selectively prepared by reacting a phosphoranylidene cephem compound with acetaldehyde in the presence of a base in a solvent mixture comprising diethyl ether, formula (I), wherein R is a carboxyl protecting group; R1 is hydrogen or R2CH2CO—; and R2 is ethyl, 2-thiophenyl, phenyl, p-hydroxyphenyl or phenoxy
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.