Flow cytometer for differentiating small particles in suspension
US7113266B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 30, 2005 |
| Grant date | Sep 26, 2006 |
| Priority date | — |
| Expiry date | Apr 14, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N15/1434
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A flow cytometer includes an optical flow cell through which particles to be characterized on the basis of at least their respective side-scatter characteristics are caused to flow seriatim. A plane-polarized laser beam produced by a laser diode is used to irradiate the particles as they pass through a focused elliptical spot having its minor axis oriented parallel to the particle flow path. Initially, the plane of polarization of the laser beam extends perpendicular to the path of particles through the flow cell. A half-wave plate or the like is positioned in the laser beam path to rotate the plane of polarization of the laser beam so that it is aligned with the path of particles before it irradiated particles moving along such path.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.