Method of testing for atopic dermatitis by measuring expression of the NOR-1 gene
US7115373B2 · kind B2 · utility
8Cited by
1References
4Claims
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Key dates
| Filing date | Jun 27, 2003 |
| Grant date | Oct 3, 2006 |
| Priority date | — |
| Expiry date | Jul 5, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/24
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Genes whose expression differ between that in eosinophils collected from atopic dermatitis patients of the exabartation stage and those of the remission stage were searched via a differential display method. As a result, NOR-1 (MINOR) gene was successfully identified whose expression significantly increased in eosinophils of patients in the remission stage, a stage associated with a decrease of eosinophils. The present inventors discovered that the gene can be successfully employed in testing for allergic diseases and screening for candidate compounds for therapeutic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.