Non-inclusion cyclodextrin complexes
US7115586B2 · kind B2 · utility
32Cited by
5References
24Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 18, 2002 |
| Grant date | Oct 3, 2006 |
| Priority date | — |
| Expiry date | Oct 18, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization of the active ingredient is enhanced by combining it with β-cyclodextrin in an aqueous complexation medium comprising β-cyclodextrin and a negatively- or positively-charged compound which forms an inclusion or non-inclusion complex with β-cyclodextrin and its inclusion complexes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.