Purine derivatives

US7115589B2 · kind B2 · utility

Assignee

• Ariad Pharmaceuticals, Inc. · US

Inventors

• Manfred Weigele · North Caldwell, US
• Tomi K. Sawyer · Southborough, US
• Regine Bohacek · Boston, US
• William C. Shakespeare · Framingham, US
• Rajeswari Sundaramoorthi · Watertown, US
• Yihan Wang · 安丰镇, CN
• David C. Dalgarno · Brookline, US
• Chester A. Metcalf, III · Needham, US

Key dates

• Filing date: Dec 18, 2000
• Grant date: Oct 3, 2006
• Expiry date: Dec 18, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/65616
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to compounds of the general formula:in which RA, RB, RC and RD are as defined herein, and to their preparation and use. In these compounds, RB is an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety which comprises one or more phosphorus-containing moieties.