Transgenic animals expressing salivary proteins
US7115795B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 20, 2000 |
| Grant date | Oct 3, 2006 |
| Priority date | — |
| Expiry date | Apr 20, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/008
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides a transgenic animal having within its genome a transgene construct for gastrointestinal tract specific expression of a protein. In a preferred embodiment, the protein is a phytase or a homologue thereof. Such proteins may be heterologous and may be specifically expressed in the salivary gland of the animal by operably linking the nucleic acid sequence encoding the protein with regulatory sequence including a salivary gland protein promoter/enhancer. Also provided are methods of expressing and producing proteins using such nucleic acid constructs. Further, antibodies specific to such proteins and immunological diagnostic kits are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.