Flow cell for optical detection having reduced sensitivity to refractive index variation
US7116423B2 · kind B2 · utility
6Cited by
1References
17Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 31, 2003 |
| Grant date | Oct 3, 2006 |
| Priority date | — |
| Expiry date | Jul 2, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/39
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus for cavity enhanced optical detection having an improved flow cell is provided. Sensitivity of the cavity resonance condition to changes in refractive index of an analyte flowing through the flow cell is reduced. More specifically, the round trip optical path defined by the resonant cavity intersects a curved cavity input mirror at a point. This point has a location on the input mirror that is substantially independent of the refractive index of the analyte. In this manner, changes in sample refractive index do not lead to misalignment of the resonant optical cavity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.