DNA molecules stabilized for propagation in bacterial cells that encode cystic fibrosis transmembrane conductance regulator
US7118911B1 · kind B1 · utility
2Cited by
2References
12Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 2, 1993 |
| Grant date | Oct 10, 2006 |
| Priority date | — |
| Expiry date | Jul 2, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are full length isolated DNAs encoding cystic fibrosis transmembrane conductance regulator (CFTR) protein and a variety of mutants thereof. Also disclosed are antibodies specific for various CFTR domains and methods for their production. Expression of CFTR from cells transformed with these CFTR genes or cDNAs demonstrate surprising CFTR intracellular distributions and results thereby providing for new diagnostic and therapeutic procedures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.