Peptides and their use as inhibitors of hepatitis C virus ns3 protease

US7119073B2 · kind B2 · utility

Assignee

• Istituto di Recerche di Biologia Molecolare P. Angeletti S.R.L. · IT

Inventors

• Stefania Colarusso · Roma, IT
• Cristina Gardelli · Pomezia, IT
• Benjamin Gerlach · Rovereto, IT
• Steven Harper · Roma, IT
• Uwe Koch · Roma, IT
• Victor Giulio Matassa · Roma, IT
• Ester Muraglia · Roma, IT
• Frank Narjes · Ariccia, IT
• Jesus Maria Ontoria Ontoria · Pomezia, IT
• Alessia Petrocchi · Roma, IT
• Simona Ponzi · Pomezia, IT
• Ian Stansfield · Roma, IT
• Vicenzo Summa · Pomezia, IT

Key dates

• Filing date: Mar 26, 2002
• Grant date: Oct 10, 2006
• Expiry date: May 12, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I), and pharmaceutically acceptable salts and esters thereof: (I); wherein Q, R2, X, Y and Z are as defined herein; are inhibitors of the hepatitis C virus (HCV) NS3 protease