Multiplexed immunohistochemical assays using molecular tags
US7122319B2 · kind B2 · utility
20Cited by
14References
10Claims
0Family size
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Key dates
| Filing date | Nov 5, 2003 |
| Grant date | Oct 17, 2006 |
| Priority date | — |
| Expiry date | Mar 31, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6823
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and compositions are provided for detection of analytes, such as cell surface moieties, preferably in multiplexed assays, such that multiple analytes can be assayed simultaneously. The methods employ analyte binding agents which are linked to oligonucleotide labels, which labels are then used for formation of cleavage structures and generation of detectable molecular tags. Preferably, multiple tags are generated per analyte binding event.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.