Isoprenoid biosynthesis

US7122331B1 · kind B1 · utility

Inventors

• Wolfgang Eisenreich · Garching bei München, DE
• Monika Fellermeier · Bocholt, DE
• Markus Fischer · Ludwigsburg, DE
• Stefan Hecht · Bad Aibling, DE
• Stefan Herz · Bocholt, DE
• Klaus Kis · Davos, CH
• Holger Lüttgen · Garching bei München, DE
• Felix Rohdich · Freising, DE
• Silvia Sagner-Grehn · Bocholt, DE
• Christoph A. Schuhr · Mannheim, DE
• Jurathip Wungsintaweekul · Hat Yai, TH
• Adelbert Bacher · Garching bei München, DE
• Meinhart H. Zenk · Chesterfield, US

Key dates

• Filing date: Aug 3, 2000
• Grant date: Oct 17, 2006
• Expiry date: Oct 7, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P23/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to enzymatic activity involved in isoprenoid biosynthesis as well as to inhibitors, notably herbicides, for enzymes in the biosynthesis of isoprenoids. More specifically, the present invention relates to screening methods for detecting such inhibitors, and to enzymatically active proteins for performing said methods as well as purified isolated DNA coding for such proteins. Moreover, the present invention relates to novel inhibitors detectable by said screening methods as well as compositions and processes for inhibiting the synthesis of isoprenoids and for controlling the growth of organisms based on said inhibiors. The invention relates also to the development of inhibitor-resistant plant enzymes and plants, plant tissues, plant seeds and plant cells.