FEN endonucleases
US7122364B1 · kind B1 · utility
73Cited by
31References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 17, 2000 |
| Grant date | Oct 17, 2006 |
| Priority date | — |
| Expiry date | Dec 12, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6813
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5′ nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.