Determining the reaction progress of graft polymerization reactions

US7122379B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Udo Wolf · Kempen, DE
• Ralf-Jurgen Born · Langenfeld, DE
• Vera Buchholz · Recklinghausen, DE
• Herbert Eichenauer · Dormagen, DE
• Eckhard Wenz · Neunburg vorm Wald, DE
• Wilhelm Bergmeier · Meerbusch, DE
• Christof Boden · Leverkusen, DE

Key dates

• Filing date: Oct 28, 2002
• Grant date: Oct 17, 2006
• Expiry date: Dec 21, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/24
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method of using Raman Spectra for determining the progress of a graft polymerization reaction is disclosed. The method entails (a) measuring at the beginning of the reaction and at a plurality of time intervals in the course of the reaction, continuously and on-site, the Raman spectrum in the wave number range of 100 to 4000 cm−1 of one or more of the monomers and/or polymers entailed in the reaction and of at least one internal standard and (b) recording the spectra and (c) adding reaction partners necessary to the reaction continuously and/or discontinuously and (d) calculating the change in concentration of the monomers and polymers by comparing the spectra of the monomers or polymers with the internal standard.