Lactam derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme
US7122560B2 · kind B2 · utility
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16Claims
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Inventor
Key dates
| Filing date | Jun 16, 2004 |
| Grant date | Oct 17, 2006 |
| Priority date | — |
| Expiry date | Aug 2, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides compounds of Formula (I):or a stereoisomer or pharmaceutically acceptable salt form thereof, wherein the variables A, B, R1, R2, U, X, Y, Z, Ua, Xa, Ya, and Za are defined are as defined herein, which are useful as inhibitors of matrix metalloproteinases (MMP), and/or TNF-α converting enzyme (TACE), or a combination thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.